What is Irritable Bowel Disease?
Irritable bowel syndrome (IBS) is a functional condition of the bowel that is diagnosed using clinical criteria. IBS affects around 11% of the population globally. Around 30% of people who experience the symptoms of IBS will consult physicians for their gastrointestinal symptoms.
These people do not have significantly different abdominal symptoms to those who do not consult, but they do have greater levels of anxiety and lower quality of life. Internationally, there is a female predominance in the prevalence of IBS. Irritable bowel syndrome (IBS) is a common condition that affects the digestive system.
Signs and Symptoms of IBS
The signs and symptoms of IBS vary but are usually present for a long time. The symptom severity can also be varied but typical common symptoms include:
- Constipation
- Diarrhoea
- Passing mucus when you pass a stool
- Bloating
- Abdominal pain, cramping or stomach pains
- Feeling nauseous
- Gas production and passing excessive amounts of wind
- Tiredness and lack and energy
- Changes in the appearance of bowel movement
- Changes in how often you are having a bowel movement
- These symptoms often come and go and are usually worse after eating and relieved by passing a stool
What Caused IBS?
The precise cause of Irritable Bowel Syndrome isn’t known. Factors that appear to play a role include:
- Muscle contractions in the intestine. The walls of the intestines are lined with layers of muscle that contract as they move food through your digestive tract. Contractions that are stronger and last longer than normal can cause gas, bloating and diarrhoea. Weak intestinal contractions can slow food passage and lead to hard, dry stools.
- Nervous system. Abnormalities in the nerves in your digestive system may cause you to experience greater than normal discomfort when your abdomen stretches from gas or stool. Poorly coordinated signals between the brain and the intestines can cause your body to overreact to changes that normally occur in the digestive process, resulting in pain, diarrhoea or constipation.
- Severe infection. IBS can develop after a severe bout of diarrhoea (gastroenteritis) caused by bacteria or a virus. IBS might also be associated with a surplus of bacteria in the intestines (bacterial overgrowth).
- Early life stress and stress levels. People exposed to stressful events, especially in childhood, tend to have more symptoms of IBS.
- Changes in gut microbes. Examples include changes in bacteria overgrowth, fungi and viruses, which normally reside in the intestines and play a key role in health. Research indicates that the microbes in people with IBS might differ from those in healthy people.
- A common factor in IBS is damage to the delicate lining of the intestines where food is absorbed. This can lead to undigested food particles passing through the barrier and interacting with the immune system. The result is inflammation and pain. There are lots of causes of intestinal damage. Food reactions, gut infections, stress and imbalances in the friendly bacteria in the gut can all play a role. The first step is to confirm that intestinal damage is present. Then it’s a case of finding and tackling the cause and using natural supplements to repair the damage. Functional testing is instrumental in uncovering the underlying causes of IBS. Stool tests can be used to assess digestive function, check for intestinal damage and identify gut infections and bacterial imbalances. Food intolerance testing can also help to identify problem foods that may be contributing to IBS – Irritable Bowel Syndrome symptoms.
Triggers
Symptoms of IBS can be triggered by:
- Food. The role of food allergy or intolerance in IBS isn’t fully understood. A true food allergy rarely causes IBS. But many people have worse IBS symptoms when they eat or drink certain foods or beverages, including wheat, dairy products, citrus fruits, beans, cabbage, milk and carbonated drinks.
- Stress. Most people with IBS experience worse or more frequent signs and symptoms during periods of increased stress. But while stress may aggravate symptoms, it doesn’t cause them.
Risk factors
Many people have occasional signs and symptoms of IBS. But you’re more likely to have the syndrome if you:
- Are young. IBS occurs more frequently in people under age 50.
- Are female. In the United States, IBS is more common among women. Estrogen therapy before or after menopause also is a risk factor for IBS.
- Have a family history of IBS. Genes may play a role, as may share factors in a family’s environment or a combination of genes and environment.
- Have anxiety, depression or other mental health issues. A history of sexual, physical or emotional abuse also might be a risk factor.
Complications
Chronic constipation or diarrhoea can cause haemorrhoids.
In addition, IBS is associated with:
- Poor quality of life. Many people with moderate to severe IBS report poor quality of life. Research indicates that people with IBS miss three times as many days from work as do those without bowel symptoms.
- Mood disorders. Experiencing the signs and symptoms of IBS can lead to depression or anxiety. Depression and anxiety also can make IBS worse.
IBS and Functional Medicine
IBS is usually a lifelong problem and it can have a big impact on your everyday life. The last 20 years have seen an increasing amount of research on the role of modifiable lifestyle factors in improving symptoms for patients with IBS. Studies on perceived food intolerance show that 64-89% of IBS patients report their symptoms to be triggered by meals or specific inflammatory foods. There is no structural change to the gut but there is a change in how the gut functions.
So approaching IBS from a functional medicine model can help. A functional medicine approach aims to restore proper function, improve health and eliminate symptoms. Functional medicine interventions might comprise solely of dietary changes. But additional options include herbal remedies, lifestyle changes and stress management techniques. By taking a complete overview of digestive health functional medicine is often more successful in providing long term IBS relief than conventional treatment. It recognises that IBS is a multi-factorial condition where the causes are different for each person. Using accurate Food Intolerance Testing may help patients identify food triggers. Interesting studies have shown reduced IBS symptoms after the introduction of low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (low-FODMAP diet ) in patients with suspected or proven fructose or lactose malabsorption. In addition, probiotics may improve IBS symptoms through manipulation of the gut microbiota.
As a functional medicine doctor, I can assess the function of organs and organ systems in your body as well which are crucial for healthy digestion. Neurotransmitter imbalances, sub-optimal stomach acid levels, liver problems, damaged gut microbiome, and hypothalamus-pituitary-adrenal axis imbalances are all potential causes of IBS that are rarely investigated.
Once the cause of your symptoms being analysed, then we plan how to control or alleviate your symptoms entirely. Not only can your symptoms disappear, but your whole body can drastically improve in its overall function.
It is very interesting that digestive disorders may have an impact on different systems in our body, developing,’brain fog’, joint aches, sleep disorders, low libido, and weight imbalances.
References
1.
Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology. 2006;130(5):1480–91. [PubMed] [Google Scholar]2.
Videlock EJ, Chang L. Irritable bowel syndrome: current approach to symptoms, evaluation, and treatment. Gastroenterol Clin North Am. 2007;36(3):665–85. x. [PubMed] [Google Scholar]3.
Pare P, Gray J, Lam S, Balshaw R, Khorasheh S, Barbeau M, et al. Health-related quality of life, work productivity, and health care resource utilization of subjects with irritable bowel syndrome: baseline results from LOGIC (Longitudinal Outcomes Study of Gastrointestinal Symptoms in Canada), a naturalistic study. Clin Ther. 2006;28(10):1726–35. discussion 1710–1. [PubMed] [Google Scholar]4.
Paterson WG, Thompson WG, Vanner SJ, Faloon TR, Rosser WW, Birtwhistle RW, et al. Recommendations for the management of irritable bowel syndrome in family practice. IBS consensus conference participants. CMAJ. 1999;161(2):154–60. [PMC free article] [PubMed] [Google Scholar]5.
Jackson JL, O’Malley PG, Tomkins G, Balden E, Santoro J, Kroenke K. Treatment of functional gastrointestinal disorders with antidepressant medications: a meta-analysis. Am J Med. 2000;108(1):65–72. [PubMed] [Google Scholar]6.
Schoenfeld P. Efficacy of current drug therapies in irritable bowel syndrome: what works and does not work. Gastroenterol Clin North Am. 2005;34(2):319–35. viii. [PubMed] [Google Scholar]7.
McFarland LV. State-of-the-art of irritable bowel syndrome and inflammatory bowel disease research in 2008. World J Gastroenterol. 2008;14(17):2625–9. [PMC free article] [PubMed] [Google Scholar]8.
Hussain Z, Quigley EM. Systematic review: complementary and alternative medicine in the irritable bowel syndrome. Aliment Pharmacol Ther. 2006;23(4):465–71. [PubMed] [Google Scholar]9.
Whitehead WE, Levy RL, Von Korff M, Feld AD, Palsson OS, Turner M, et al. The usual medical care for irritable bowel syndrome. Aliment Pharmacol Ther. 2004;20(11–12):1305–15. [PubMed] [Google Scholar]10.
Thompson WG, Heaton KW, Smyth GT, Smyth C. Irritable bowel syndrome in general practice: prevalence, characteristics, and referral. Gut. 2000;46(1):78–82. [PMC free article] [PubMed] [Google Scholar]11.
Lacy BE, Weiser K, Noddin L, Robertson DJ, Crowell MD, Parratt-Engstrom C, et al. Irritable bowel syndrome: patients’ attitudes, concerns and level of knowledge. Aliment Pharmacol Ther. 2007;25(11):1329–41. [PubMed] [Google Scholar]12.
Dhaliwal SK, Hunt RH. Doctor-patient interaction for irritable bowel syndrome in primary care: a systematic perspective. Eur J Gastroenterol Hepatol. 2004;16(11):1161–6. [PubMed] [Google Scholar]13.
Pittler MH, Ernst E. Peppermint oil for irritable bowel syndrome: a critical review and metaanalysis. Am J Gastroenterol. 1998;93(7):1131–5. [PubMed] [Google Scholar]14.
Spanier JA, Howden CW, Jones MP. A systematic review of alternative therapies in the irritable bowel syndrome. Arch Intern Med. 2003;163(3):265–74. [PubMed] [Google Scholar]15.
McFarland LV, Dublin S. Meta-analysis of probiotics for the treatment of irritable bowel syndrome. World J Gastroenterol. 2008;14(17):2650–61. [PMC free article] [PubMed] [Google Scholar]16.
Bijkerk CJ, Muris JW, Knottnerus JA, Hoes AW, de Wit NJ. Systematic review: the role of different types of fibre in the treatment of irritable bowel syndrome. Aliment Pharmacol Ther. 2004;19(3):245–51. [PubMed] [Google Scholar]17.
Bian Z, Wu T, Liu L, Miao J, Wong H, Song L, et al. Effectiveness of the chinese herbal formula TongXieYaoFang for irritable bowel syndrome: a systematic review. J Altern Complement Med. 2006;12(4):401–7. [PubMed] [Google Scholar]18.
Webb AN, Kukuruzovic RH, Catto-Smith AG, Sawyer SM. Hypnotherapy for treatment of irritable bowel syndrome. Cochrane Database Syst Rev. 2007;4(4):CD005110. [PubMed] [Google Scholar]19.
Gholamrezaei A, Ardestani SK, Emami MH. Where does hypnotherapy stand in the management of irritable bowel syndrome? A systematic review. J Altern Complement Med. 2006;12(6):517–27. [PubMed] [Google Scholar]20.
Wilson S, Maddison T, Roberts L, Greenfield S, Singh S Birmingham IBS Research Group. Systematic review: the effectiveness of hypnotherapy in the management of irritable bowel syndrome. Aliment Pharmacol Ther. 2006;24(5):769–80. [PubMed] [Google Scholar]21.
Whitehead WE. Hypnosis for irritable bowel syndrome: the empirical evidence of therapeutic effects. Int J Clin Exp Hypn. 2006;54(1):7–20. [PubMed] [Google Scholar]22.
Drossman DA, Toner BB, Whitehead WE, Diamant NE, Dalton CB, Duncan S, et al. Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders. Gastroenterology. 2003;125(1):19–31. [PubMed] [Google Scholar]23.
Boyce PM, Talley NJ, Balaam B, Koloski NA, Truman G. A randomized controlled trial of cognitive behavior therapy, relaxation training, and routine clinical care for the irritable bowel syndrome. Am J Gastroenterol. 2003;98(10):2209–18. [PubMed] [Google Scholar]24.
Kennedy T, Jones R, Darnley S, Seed P, Wessely S, Chalder T. Cognitive behaviour therapy in addition to antispasmodic treatment for irritable bowel syndrome in primary care: randomised controlled trial. BMJ. 2005;331(7514):435. [PMC free article] [PubMed] [Google Scholar]25.
Van Dulmen AM, Fennis JF, Bleijenberg G. Cognitive-behavioral group therapy for irritable bowel syndrome: effects and long-term follow-up. Psychosom Med. 1996;58(5):508–14. [PubMed] [Google Scholar]26.
Blanchard EB, Lackner JM, Sanders K, Krasner S, Keefer L, Payne A, et al. A controlled evaluation of group cognitive therapy in the treatment of irritable bowel syndrome. Behav Res Ther. 2007;45(4):633–48. [PubMed] [Google Scholar]27.
Zuckerman MJ. The role of fiber in the treatment of irritable bowel syndrome: therapeutic recommendations. J Clin Gastroenterol. 2006;40(2):104–8. [PubMed] [Google Scholar]28.
Manning AP, Heaton KW, Harvey RF. Wheat fibre and irritable bowel syndrome. A controlled trial. Lancet. 1977;2(8035):417–8. [PubMed] [Google Scholar]29.
Quartero AO, Meineche-Schmidt V, Muris J, Rubin G, de Wit N. Bulking agents, antispasmodic and antidepressant medication for the treatment of irritable bowel syndrome. Cochrane Database Syst Rev. 2005;2(2):CD003460. [PubMed] [Google Scholar]30.
Miller V, Lea R, Agrawal A, Whorwell PJ. Bran and irritable bowel syndrome: the primary-care perspective. Dig Liver Dis. 2006;38(10):737–40. [PubMed] [Google Scholar]31.
Francis CY, Whorwell PJ. Bran and irritable bowel syndrome: time for reappraisal. Lancet. 1994;344(8914):39–40. [PubMed] [Google Scholar]32.
Snook J, Shepherd HA. Bran supplementation in the treatment of irritable bowel syndrome. Aliment Pharmacol Ther. 1994;8(5):511–4. [PubMed] [Google Scholar]33.
Kligler B, Chaudhary S. Peppermint oil. Am Fam Physician. 2007;75(7):1027–30. [PubMed] [Google Scholar]34.
Cappello G, Spezzaferro M, Grossi L, Manzoli L, Marzio L. Peppermint oil (mintoil) in the treatment of irritable bowel syndrome: a prospective double blind placebo-controlled randomized trial. Dig Liver Dis. 2007;39(6):530–6. [PubMed] [Google Scholar]35.
Kline RM, Kline JJ, Di Palma J, Barbero GJ. Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children. J Pediatr. 2001;138(1):125–8. [PubMed] [Google Scholar]36.
Liu JH, Chen GH, Yeh HZ, Huang CK, Poon SK. Enteric-coated peppermint-oil capsules in the treatment of irritable bowel syndrome: a prospective, randomized trial. J Gastroenterol. 1997;32(6):765–8. [PubMed] [Google Scholar]38.
Dew MJ, Evans BK, Rhodes J. Peppermint oil for the irritable bowel syndrome: a multicentre trial. Br J Clin Pract. 1984;38(11–12):394–8. [PubMed] [Google Scholar]39.
Lawson MJ, Knight RE, Tran K, Walker G, Roberts-Thomson IC. Failure of enteric-coated peppermint oil in the irritable bowel syndrome: a randomized, double-blind crossover study. J Gastroenterol Hepatol. 1988;3(3):235–8. [Google Scholar]40.
Nash P, Gould SR, Bernardo DE. Peppermint oil does not relieve the pain of irritable bowel syndrome. Br J Clin Pract. 1986;40(7):292–3. [PubMed] [Google Scholar]41.
Lu W, Kaptchuk TJ, Wong H, George C. Chinese herbal medicine for irritable bowel syndrome. JAMA. 1999;282(11):1035–7. [PubMed] [Google Scholar]42.
Bensoussan A, Talley NJ, Hing M, Menzies R, Guo A, Ngu M. Treatment of irritable bowel syndrome with chinese herbal medicine: a randomized controlled trial. JAMA. 1998;280(18):1585–9. [PubMed] [Google Scholar]43.
Wang G, Li TQ, Wang L, Xia Q, Chang J, Zhang Y, et al. Tong-xie-ning, a chinese herbal formula, in treatment of diarrhea-predominant irritable bowel syndrome: a prospective, randomized, double-blind, placebo-controlled trial. Chin Med J (Engl) 2006;119(24):2114–9. [PubMed] [Google Scholar]44.
Leung WK, Wu JC, Liang SM, Chan LS, Chan FK, Xie H, et al. Treatment of diarrhea-predominant irritable bowel syndrome with traditional chinese herbal medicine: a randomized placebo-controlled trial. Am J Gastroenterol. 2006;101(7):1574–80. [PubMed] [Google Scholar]45.
Sallon S, Ben-Arye E, Davidson R, Shapiro H, Ginsberg G, Ligumsky M. A novel treatment for constipation-predominant irritable bowel syndrome using padma lax, a tibetan herbal formula. Digestion. 2002;65(3):161–71. [PubMed] [Google Scholar]46.
Madisch A, Holtmann G, Plein K, Hotz J. Treatment of irritable bowel syndrome with herbal preparations: results of a double-blind, randomized, placebo-controlled, multi-centre trial. Aliment Pharmacol Ther. 20041;19(3):271–9. [PubMed] [Google Scholar]47.
Liu JP, Yang M, Liu YX, Wei ML, Grimsgaard S. Herbal medicines for treatment of irritable bowel syndrome. Cochrane Database Syst Rev. 2006;1(1):CD004116. [PubMed] [Google Scholar]48.
Shi J, Tong Y, Shen JG, Li HX. Effectiveness and safety of herbal medicines in the treatment of irritable bowel syndrome: a systematic review. World J Gastroenterol. 2008;14(3):454–62. [PMC free article] [PubMed] [Google Scholar]49.
Quigley EM, Flourie B. Probiotics and irritable bowel syndrome: a rationale for their use and an assessment of the evidence to date. Neurogastroenterol Motil. 2007;19(3):166–72. [PubMed] [Google Scholar]50.
Camilleri M. Probiotics and irritable bowel syndrome: rationale, putative mechanisms, and evidence of clinical efficacy. J Clin Gastroenterol. 2006;40(3):264–9. [PubMed] [Google Scholar]52.
Lackner JM, Mesmer C, Morley S, Dowzer C, Hamilton S. Psychological treatments for irritable bowel syndrome: a systematic review and meta-analysis. J Consult Clin Psychol. 2004;72(6):1100–13. [PubMed] [Google Scholar]53.
Whorwell PJ. Review article: the history of hypnotherapy and its role in the irritable bowel syndrome. Aliment Pharmacol Ther. 2005;22(11–12):1061–7. [PubMed] [Google Scholar]54.
Whorwell PJ, Prior A, Faragher EB. Controlled trial of hypnotherapy in the treatment of severe refractory irritable-bowel syndrome. Lancet. 1984;2(8414):1232–4. [PubMed] [Google Scholar]55.
Galovski TE, Blanchard EB. The treatment of irritable bowel syndrome with hypnotherapy. Appl Psychophysiol Biofeedback. 1998;23(4):219–32. [PubMed] [Google Scholar]56.
Palsson OS, Turner MJ, Johnson DA, Burnelt CK, Whitehead WE. Hypnosis treatment for severe irritable bowel syndrome: investigation of mechanism and effects on symptoms. Dig Dis Sci. 2002;47(11):2605–14. [PubMed] [Google Scholar]57.
Roberts L, Wilson S, Singh S, Roalfe A, Greenfield S. Gut-directed hypnotherapy for irritable bowel syndrome: piloting a primary care-based randomised controlled trial. Br J Gen Pract. 2006;56(523):115–21. [PMC free article] [PubMed] [Google Scholar]58.
Vlieger AM, Menko-Frankenhuis C, Wolfkamp SC, Tromp E, Benninga MA. Hypnotherapy for children with functional abdominal pain or irritable bowel syndrome: a randomized controlled trial. Gastroenterology. 2007;133(5):1430–6. [PubMed] [Google Scholar]59.
Gonsalkorale WM, Miller V, Afzal A, Whorwell PJ. Long term benefits of hypnotherapy for irritable bowel syndrome. Gut. 2003;52(11):1623–9. [PMC free article] [PubMed] [Google Scholar]60.
Gonsalkorale WM, Houghton LA, Whorwell PJ. Hypnotherapy in irritable bowel syndrome: a large-scale audit of a clinical service with examination of factors influencing responsiveness. Am J Gastroenterol. 2002;97(4):954–61. [PubMed] [Google Scholar]62.
Palsson OS. Should we incorporate psychological care into the management of IBS? Nat Clin Pract Gastroenterol Hepatol. 2006;3(9):474–5. [PubMed] [Google Scholar]64.
Lim B, Manheimer E, Lao L, Ziea E, Wisniewski J, Liu J, et al. Acupuncture for treatment of irritable bowel syndrome. Cochrane Database Syst Rev. 2006;4(4):CD005111. [PubMed] [Google Scholar]65.
Schneider A, Enck P, Streitberger K, Weiland C, Bagheri S, Witte S, et al. Acupuncture treatment in irritable bowel syndrome. Gut. 2006;55(5):649–54. [PMC free article] [PubMed] [Google Scholar]66.
Forbes A, Jackson S, Walter C, Quraishi S, Jacyna M, Pitcher M. Acupuncture for irritable bowel syndrome: a blinded placebo-controlled trial. World J Gastroenterol. 2005;11(26):4040–4. [PMC free article] [PubMed] [Google Scholar]67.
Lowe C, Depew W, Vanner S. A placebo-controlled, double-blind trial of acupuncture in the treatment of irritable bowel syndrome (IBS) Gastroenterology. 2000;118(4 Suppl 2):A3168. [Google Scholar]68.
Liu GZ. Treatment of acupuncture and moxibustion plus psychotherapy for irritable bowel syndrome [Chinese] Zhongguo Zhen Jiu. 1997;10:611–2. [Google Scholar]69.
Liao YC. Acupuncture treatment for 132 cases of irritable bowel syndrome. Clin J Acupunct Moxibustion. 2000;16(6):13. [Google Scholar]70.
Schneider A, Streitberger K, Joos S. Acupuncture treatment in gastrointestinal diseases: a systematic review. World J Gastroenterol. 2007;13(25):3417–24. [PMC free article] [PubMed] [Google Scholar]